A CME Regional Symposium

Addresing the Natural History of Type 2 Diabetes

Practical Approaches to Controlling Fasting & Postprandial Glucose Levels

When it comes to the natural progression of type 2 diabetes, the endogenous ability of the pancreas to secrete insulin diminishes over time. Initiation of prandial insulin in type 2 diabetes, typically after basal insulin has been added, is often a stepwise approach and, unfortunately, education and training for healthcare providers (HCPs) regarding how best to initiate and titrate basal and prandial insulin has been broadly deficient or absent. With the advent and availability of new insulin preparations as well as GLP-1 receptor agonists, which serve an important role in controlling post-prandial glucose levels, there is the urgent need for health care provider education on all aspects of glycemic control-- including initiation and titration of both basal and prandial insulin as well as GLP-1 receptor agonists.

Educating health care providers on the clinically important properties of these new insulins, familiarizing providers with their pharmacokinetics, pharmacodynamics, how they should be initiated, titrated, and exchanged for other insulins in appropriate patients who may benefit from these newer formulations will help improve patients glycemic control, including time in range, and reducing the incidence of hypoglycemia.

Acknowledgment of Commercial Support

  • This activity is supported by an educational grant from Sanofi US.


It is the policy of the University of California, San Diego School of Medicine to ensure balance, independence, objectivity and scientific rigor. All persons involved in the selection, development and presentation of content are required to disclose any real or apparent conflicts of interest. All conflicts of interest will be resolved prior to an educational activity being delivered to learners through one of the following mechanisms: 1) altering the financial relationship with the commercial interest, 2) altering the individual’s control over CME content about the products or services of the commercial interest, and/or 3) validating the activity content through independent peer review. All persons are also required to disclose any discussions of off label/unapproved uses of drugs or devices. Persons who refuse or fail to disclose will be disqualified from participating in the CME activity.

Cultural and Linguistic Competency

This activity is in compliance with California Assembly Bill 1195 which requires continuing medical education activities with patient care components to include curriculum in the subjects of cultural and linguistic competency. Cultural competency is defined as a set of integrated attitudes, knowledge, and skills that enables health care professionals or organizations to care effectively for patients from diverse cultures, groups, and communities. Linguistic competency is defined as the ability of a physician or surgeon to provide patients who do not speak English or who have limited ability to speak English, direct communication in the patient’s primary language. Cultural and linguistic competency was incorporated into the planning of this activity. Additional resources can be found on the UC San Diego CME website.