You Don't Have to Marry Your CGM–Explore the CGM Dating Scene!
Jeremy Pettus, MD swipes through the current continuous glucose monitor (CGM) lineup to see how much has changed since he last picked one!
Dr. Jeremy Pettus gets dumped by his continuous glucose monitor (CGM)…over text! The sensor signs off by sending him a link to CGMder, a dating app where CGMs have profiles and Jeremy can see what each one brings before he commits to something more serious.
When considering the best CGM device for you and your lifestyle, it almost feels like you are entering the dating game—you have to decide which traits matter to you, which ones you can live without, and how well the match works in real life. Nothing about the choice has to be permanent. You can try something new, switch back, or keep looking for the best fit.
That kind of flexibility is very recent. With today’s leading CGMs accurate enough to support insulin-dosing decisions, accuracy is no longer the deciding factor. The right choice is much more personal, including which insulin pump you use, your history with a sensor you already trust, help with basal insulin titration, personalized food-impact predictions, and next-generation continuous ketone monitoring that is moving closer to availability.
by the numbers
10 years
This is a typical timeframe for a new therapy to move from discovery, through animal studies and three phases of human trials, to an FDA decision.
3 phases...
Of human clinical trials stand between a promising discovery and an FDA review.
Over 50 people...
Have taken part in the phase 3 program for the most advanced stem-cell-derived approach discussed in this update.
3 hormones
Islet cells produce insulin, amylin, and glucagon, not insulin alone, which is part of what makes replacing them so appealing.
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Worth Knowing Before You Watch
- Islet cells do more than make insulin – they also produce hormones like amylin and glucagon that help the body manage blood sugar, which is why replacing the whole cell matters more than replacing insulin alone.
- The cells can come from two very different sources – donated tissue from deceased donors, which is a limited supply, or cells grown in the lab from stem cells, which offers offers unlimited access.
- Where the cells are placed matters – researchers are studying infusion into the blood vessel that feeds the liver, along with other sites like tissue under the skin and even muscle.
- The immune system is the central challenge – the body attacks transplanted cells, so every approach has to solve the problem of protecting them, and this is where the leading programs differ most.
- Durability is still an open question – even the most promising results raise the question of how long transplanted cells keep working, and that is one of the things researchers are watching very closely.
INTERESTED TO LEarn More about this topic?
What would be your choice and why? What features do you like/anticipate the most! Let us know in the comments below!
Supported by an unrestricted educational grant from Mannkind Corporation.
The eversense 365 sounds great for weartime but the implanting under my skin is where I draw the line, so I would choose the minimed instinct.
Thankfully we have several options, so everyone can choose the system that best suits their needs and lifestyle!