Still Using the Rule of 500? How Optimized Omnipod 5 Settings Can Push TIR to 80% or Higher

A Practical Guide for Healthcare Providers: Successfully Adjusting the Target Glucose, Insulin-to-Carb Ratio, Correction Factor, and Duration of Insulin Action

In this video: 
  • Why the 500 rule and 1800 rule may be holding your patients back — and what to use instead
  • The Target Glucose setting change that can add up to 2.5 hours of TIR per day with no meaningful increase in hypoglycemia
  • How more aggressive bolus settings can improve postprandial blood sugar and strengthen the algorithm itself
  • Upcoming Omnipod 5 updates, including a new 100 mg/dL target option and FreeStyle Libre 3 Plus integration

Despite advances in diabetes devices and therapies, many patients are still not meeting their glycemic goals. While patient behavior and lifestyle modifications matter, the insulin pump settings themselves play a major role. Real-world evidence shows that when Omnipod 5 settings are optimized appropriately, TIR can reach 80% or higher. In this video, Dr. Steve Edelman and Dr. Jeremy Pettus — both endocrinologists and people living with type 1 diabetes — share the specific adjustments they recommend in their own practice. Simple, evidence-based changes you can make at your next visit to help close the gap between where your patients are and where they could be.

See an official clinical guide on Omnipod 5 optimization.

What Target Glucose setting are you currently using for most of your Omnipod 5 patients? Let us know in the comments!

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