Ep 91: 2026 Diabetes Predictions: Retatrutide, Oral GLP-1s & Stem Cell Breakthroughs… and more!
In this episode you will explore:
- Disease-Modifying Therapies for T1D: Preserving beta cell function after T1D diagnosis and why this represents a major shift in treatment goals.
- New Medications for Type 2 Diabetes: Oral GLP-1s, dual- and triple-agonist therapies, and what they may offer beyond current options.
- GLP-1s in Type 1 Diabetes: Where the research stands, off-label use today, and what future approvals could look like.
- Once-Weekly Basal Insulin: Why it’s promising for type 2 diabetes and who it’s best suited for.
- Inhaled Insulin Updates: New dosing guidance and expanded use cases.
- Continuous Ketone Monitoring: How this technology could improve safety and open doors for additional therapies in T1D.
- Cure-Oriented Research: Stem cell and gene therapy approaches that aim to restore insulin production.
- The Big Picture in 2026: Why 2026 represents real momentum — and what it could mean for access, outcomes, and quality of life.
What new advancements are actually coming in diabetes care in 2026 and what’s in store in the near future? In this episode, Dr. Steve Edelman and Dr. Jeremy Pettus both take a look at the diabetes treatments and technologies they believe are most likely to arrive in 2026.
Together, they walk through emerging therapies for both type 1 and type 2 diabetes, focusing on developments that are no longer theoretical but actively moving through late-stage trials and regulatory review. The conversation covers disease-modifying treatments, next-generation medications, and technology advances that could meaningfully change daily diabetes management.
Great content. Thanks
Appreciate you listening!
My doctor put me on ozempic after 3 wks i was on 20I think of the shot. And it made me terribly sick. I kept vomiting, I kept having acid reflux. So bad that even my nose burned, I was in the hospital for a panic attack or stress, or whatever you call it. And the doctor for that, also called in a gastrologist, and said that I had severe burning in my throat. And in my esophagus, because of the ozempic, when they did in endoscopy, I am also on a blood thinner called xarelto and was on guardians at the same time
I wish I could talk to one of you personally on the phone cause most of the time. These doctors in Colorado don’t know what the heck they are doing especially with the diabetes drugs
If you can help me in any way right now. I am on tragenta, and my diabetes numbers are totally out of control. I see my diabetic doctor on February 6th. She has me on tragenta, and I don’t think that is doing any good at all.
Hi there,
We’re so sorry for what you are going through. Dr. Edelman does know two very good endocrinologists in Colorado you could try reaching out to: Dr. Sarah Bull in Denver and Dr. Neda Rasouli in Aurora. Hopefully one of them will be able to help you.
ThankYou
In 2022, my diabetes was out of control. My doctor prescribed Ozemptic. I had the same symptoms (maybe not as bad) that I thought vomiting, etc. was how I’ll get my diabetes under control. However, I called my doctor to prescribe something else. His response, hang in there, it takes at least 30 days for the side affects to subside@ i drank more water, ate non’greasy foods, stayed close to bathrooms, etc. Lo and behold, by the end of the 30th day, back to normal! Except my body/appetite wasn’t! Not only did I Lose 25% (35 lbs) of body weight, but my whole health change for the best! I’m no longer taking insulin, lowered AC1, cholesterol, high blood pressure, etc.! Cannot say enough! Try if you must, the benefits are phenomenal! Praying for your health!!
That’s awesome! 🙌 Thanks for sharing your experience and RESULTS!
Thank you, it was great! I’m a Type 1, I have a Tandem pump, and a Dexcom G7 for my meter. I got diabetes when I was 13, and I am now 69, and functioning great!
That’s awesome! 🙌